You need bruises to know blessings and I have known both.

Pain and disease awaken us to convictions which are necessary to our moral condition.

Those who do not feel pain seldom think that it is felt.

The measure of a man is not whether he has pain, for this all men must have in common. The measure of a man is what gives him pain.

The stabbing horror of life is not contained in calamities and disasters, because these things wake one up and one gets very familiar and intimate with them and finally they become tame again ... No, it is more like being in a hotel room in Hoboken, let us say, and just enough money in one's pocket for another meal.

Is there any stab as deep as wondering where and how much you failed those you loved?

There is advantage in the wisdom won from pain.

Out of pain and problems have come the sweetest songs, the most poignant poems, the most gripping stories.

Pain is life - the sharper, the more evidence of life.

When the head aches, all the members share the pain.